The present study was carried out on phytochemical constituents and antimicrobial properties of seagrass species Cymodocea serrulata and Halodule pinifolia against ten clinical pathogens. The sea grasses were extracted with three different solvents such as acetone, methanol and aqueous. The qualitative analysis of phytochemicals reveals in the presence of phenols, flavonoids, alkaloids, glycosides and steroids in both species. The antimicrobial effect of all the three extracts confirms significant activity against both Gram positive and Gram negative bacteria compared to Gentamicin (10µg/disc). The results of present study were concluded that seagrass species Cymodocea serrulata and Halodule pinifolia possess potential antibiotic against clinical pathogens.
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